双背压凝汽器抽空气系统的改造及效益分析

分析了某电厂600MW超临界机组双背压凝汽器背压差偏小的原因,为发挥双背压凝汽器的技术优势,对其抽空气系统进行了改造.通过时改造前后抽空气系统不同运行方式的对比试验,证明对双背压凝汽器抽空气系统连接方式的改造,技术上可行,经济效果明显,值得其他同类机组借鉴.     

Real-world utilization of molecular diagnostic testing and matched drug therapies in the treatment of metastatic cancers

Aims: To assess the frequency of biopsies and molecular diagnostic testing (human DNA/RNA analysis), anti-cancer drug use (genomically-matched targeted therapy [GMTT], unmatched targeted therapy [UTT], endocrine therapy [ET], and chemotherapy [CT]), and medical service costs among adults with metastatic cancer.

Methods: Adults diagnosed with metastatic breast, non-small cell lung (NSCLC), colorectal, head and neck, ovarian, and uterine cancer (2010Q1–2015Q1) were identified in the OptumHealth Care Solutions claims database and followed from first metastatic diagnosis for ≥1 month and until the end of data availability. Utilization was assessed for each cancer cohort (all and patients aged ≥65 years); per-patient-per-month (PPPM) medical service costs were assessed for all patients. Testing frequency estimates were applied to Surveillance, Epidemiology, and End Results Program data to estimate the number of untested patients (2010–2014).

Results: Patients with metastatic cancer (n?=?8,193; breast [n?=?3,414], NSCLC [n?=?2,231], colorectal [n?=?1,611], head and neck [n?=?511], ovarian [n?=?275], and uterine [n?=?151]) were 63 years old (mean), with 11.1–22.2 months of observation. Biopsy and molecular diagnostic testing frequencies ranged from 7% (uterine) to 73% (ovarian), and from 34% (head and neck) to 52% (breast), respectively. Few were treated with GMTT (breast, 11%; NSCLC, 9%; colorectal, 6%). Treatment with UTT ranged from 0.7% (uterine) to 21% (colorectal). Biopsy, diagnostic testing, and anti-cancer drug therapy were less frequent for those ≥65 years. Medical service costs (PPPM, mean) ranged from $6,618 (head and neck) to $9,940 (ovarian). The estimated number of untested new patients with metastatic cancer was 636,369 (all) and 341,397 (≥65).

Limitations: In addition to the limitations of claims analyses, diagnostic testing frequency may be under-estimated if patients underwent testing prior to study inclusion.

Conclusions: The low frequency of molecular diagnostic testing suggests there are opportunities to better inform management of patients with advanced cancer, particularly decisions to treat with GMTT.     

TOOR: A Novel Product Title Optimization Method Based on Online Reviews in E-commerce

Titles of online products play an important role in attracting consumers and promoting product sales in e-commerce. However, current online product titles only cover basic features and cannot reflect the preferences of consumers exactly. To address this problem, this research proposed an online title optimization method based on the analysis of online reviews, which is called TOOR (Title Optimization based on Online Reviews). In this research, we analyzed and compared product features extracted from online product titles and online reviews from the point of view of consumers and applied features extracted from reviews to title optimization. In order to verify the effectiveness of the proposed method, two experiments were conducted in this paper, selecting four typical smartphones as experiment samples and Taobao.com as the data resources. The experimental results indicated that features extracted from online reviews can better reflect the consumers’ concern, and the titles optimized by the TOOR method are more appealing to consumers and have higher click-through rates.     

芦丁的提取及其在小鼠试验中表现的生物活性综述

芦丁作为黄酮类主要成分的代表,受到科研界的高度重视,目前芦丁的提取应用技术比较成熟。将从芦丁的来源,提取技术以及芦丁在小鼠试验中表现出的生物活性,芦丁的研究前景几个方面进行综述。重点研究芦丁的生物活性在小白鼠体内的表现。为芦丁的工业生产和应用提供参考。     

气相色谱法测定水果、蔬菜中多种拟除虫菊酯类农药残留

【目的】建立快速、准确测定水果、蔬菜中4种拟除虫菊酯类农药残留量的方法。【方法】微波加速反应系统提取农药残留,固相萃取（SPE）柱净化,毛细管柱气相色谱法-μECD检测器测定。【结果】可同时分离检测4种拟除虫菊酯类农药残留,检出限均可达到0．00μg／mL,甲氰菊酯在0．001-5μg／mL范围内、其他3种菊酯在0．001～10μg/mL范围内线性关系良好,相关系数r〉0．9990;回收率为76．2％-105．9％,相对标准偏差为3．4％-12．0％。【结论】本方法灵敏度高、净化效果好、节省时间。     

反相高效液相色谱“蓝色素”快速检测方法研究

本研究采用反相高效液相色谱法,系统研究了蓝色素的分离提取方法,确定了蓝色素测定的色谱条件,在此基础上进行了色谱测定的方法学研究,明确了蓝色素的线性范围、精密度及回收率,建立了最佳的定量方法。     

食品包装材料中邻苯二甲酸酯增塑剂残留的检测

针对食品包装材料中邻苯二甲酸酯（PAEs）增塑剂残留,采用加速溶剂萃取（ASE）和GC／MS联用技术分析5种PAEs（DMP,DEP,DBP,BBP,DEHP）,结果表明加速溶剂萃取用于食品包装材料中PAEs的提取,最佳温度条件为120℃,最佳循环次数为3次。方法检出限达到0．1mg／kg．回收率达到95．5％-99．8％;并且具有很好的重现性和精密度。     

Fe-Cr纤维提取工艺与磁性研究

为解决Fe-Cr纤维提取过程中容易造成空气污染的问题,使得到的纤维具有较高的磁学性能,采用化学萃取法腐蚀掉Cu-13Fe-2Cr原位复合材料中的铜基体,制备了Fe-Cr金属纤维;通过调整硝酸与双氧水比例抑制NO2的产生;通过改变清洗方式使纤维具有较高的磁性。用SEM进行了形貌观察和成分能谱分析,用振动样品磁强计VSM作出了纤维的磁滞回线。结果表明,NO2被成功抑制,纤维的比饱和磁化强度保持在150 A.m2.kg-1左右。     

乙醇浸提法提取红薯茎叶总黄酮的研究

采用乙醇浸提法提取红薯茎叶中的黄酮,在前期单因素研究基础上,进行正交设计试验,得出乙醇浸提法提取红薯茎叶中黄酮的最佳工艺条件:乙醇浓度80%、提取时间3 h、提取温度70℃、料液比1∶40,在该条件下黄酮的提取率为0.831 6%。     

QuEChERS—气相色谱法鱼肉中多氯联苯残留分析方法的研究

为建立QuEChERS—气相色谱鱼肉中多氯联苯残留的分析方法,取样品以1%冰乙酸的15 m L乙腈提取,采用分散型固相萃取,萃取净样品后,提取液氮吹浓缩后用正己烷定容,过滤膜,上GC-ECD检测。结果显示:样品加标回收率在76.4%~104.4%,相对标准偏差RSD在1.2%~3.6%,当取样量为3 g时,检出限在0.2~0.5μg/kg。